Table 2.
Associations between functional connectivity and dimensional traits in the current cohort
| Dimensional trait scale | Global connectivity across all channels | Global connectivity across selected channels | |
|---|---|---|---|
| HR-ASD infants N = 12 | ADI-R Social and | r = 0.20, | r = 0.39, |
| communicationa | p = 0.526 | p = 0.211 | |
| ADI-R | r = 0.52, | r = 0.60b,c | |
| RRBd | p = 0.086 | p = 0.037 | |
| ADOS-2 | r = –0.09, | r = –0.01, | |
| Social affecte | p = 0.776 | p = 0.983 | |
| ADOS-2 | r = –0.06, | r = 0.08, | |
| RRBf | p = 0.847 | p = 0.797 | |
| All HR infants N = 79 | ADI-R Social and | r = 0.12g, | r = 0.03, |
| communication | p = 0.300 | p = 0.788 | |
| ADI-R | r = 0.06g, | r = –0.02, | |
| RRB | p = 0.584 | p = 0.890 | |
| ADOS-2 | r = –0.07, | r = –0.05, | |
| Social affect | p = 0.523 | p = 0.664 | |
| ADOS-2 | r = 0.13, | r = 0.13, | |
| RRB | p = 0.254 | p = 0.259 |
Spearman’s rho values are represented by r. P-values are 2-tailed. The correlations are given for functional connectivity calculated across all channels and across the selected channels. Correlations reaching significance in the current, as well as previous cohort printed in bold
aAutism Diagnostic Interview–Revised, sum of the Social Algorithm Total and Communication Algorithm Total at 36 months
bCorrelations expected to reach significance based on the previous study
cCorrelation reaching significance at 0.05 significance level (uncorrected for multiple comparisons)
dAutism Diagnostic Interview–Revised, Behaviours/ Repetitive Interests Algorithm Total 36 months
eAutism Diagnostic Observation Schedule–2, Social Affect Total 36 months
fAutism Diagnostic Observation Schedule–2, Restricted and Repetitive Behaviours Total 36 months
gCorrelations expected to show a trend based on the previous study