Figure 1.
Snap29 conservation and expression in zebrafish. (A) Protein sequence alignment of human and zebrafish Snap29 from UniProt (http://www.uniprot.org). Red triangles refer to two SNAP29 mutations described in CEDNIK patients. Amino acid residues are shaded according to their degree of conservation, as described in the legend. (B) Whole-mount in situ hybridization with snap29 antisense and sense probes on zebrafish embryos at the indicated developmental stages.