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. 2019 Jan 18;10(2):52. doi: 10.1038/s41419-018-1288-0

Fig. 2. CBX8 promotes proliferative capacity of HCC cells both in vitro and in vivo.

Fig. 2

a Proliferation of HepG2-CBX8, Huh7-CBX8, and their control cells was examined by CCK-8 assay. b Proliferation of SMMC-7721-shCBX8, Sk-Hep-1-shCBX8, and their control cells was examined by CCK-8 assay. c Images (left), growth (middle), and weight (right) of tumors following subcutaneous injection of HepG2-CBX8 or control cells. d Images (left), growth (middle), and weight (right) of tumors following subcutaneous injection of SMMC-7721-shCBX8 or control cells. e Representative images of CBX8 and Ki-67 immunostaining in HepG2-CBX8 and the control xenografts. f Ki-67 immunostaining in SMMC-7721-shCBX8 and the control xenografts. **p < 0.01. CBX8 Chromobox homolog 8, HCC hepatocellular carcinoma, CCK-8 Cell Counting Kit-8