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. 2019 Jan 18;10(2):52. doi: 10.1038/s41419-018-1288-0

Fig. 4. CBX8 promotes migratory, invasive, and metastatic capacities of HCC cells.

Fig. 4

a HepG2-CBX8 and the control cells were subjected to transwell migration and Matrigel invasion assays. Quantification of migrated cells through the membrane and invaded cells through either the membrane or Matrigel for each cell line are shown as a proportion of the vector control. b SMMC-7721-shCBX8 and the control cells were subjected to transwell migration and Matrigel invasion assays. Quantification of migrated cells through either the membrane or Matrigel for each cell lines is shown as proportions of their controls. c Number of metastatic foci per section in lungs from individual mouse with injection of HepG2-CBX8 or its control cells were determined. A representative stain and quantification of the results are shown. d Number of metastatic foci per section in lungs from individual mice injected with SMMC-7721-shCBX8 or its control cells were determined. A representative stain and quantification of the results are shown. ** p < 0.01. CBX8 Chromobox homolog 8, HCC hepatocellular carcinoma