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. 2019 Feb 4;9:1119. doi: 10.1038/s41598-018-37825-8

Table 2.

MRI protocol. The abbreviation YS denotes the parameters used for the acquisitions from the young cohort, ES from the elderly one, and P for the patients, where they differed between them.

Sequence 3T T2-w 3T T2-w CISS 3T MPRAGE 3T DWI 7T MP2RAGE 7T SWI
Scanning Machine (Siemens) YS: Tim Trio YS: Tim Trio YS: Tim Trio;ES,P: Prisma YS: Tim Trio; ES,P: Prisma Magnetom (head only) Magnetom (head only)
Resolution, mm3 YS: 0.5 × 0.5 × 1.0 YS: 0.4 × 0.4 × 0.4 1.0 × 1.0 × 1.0 2.2 × 2.2 × 2.2 YS1, YS2, ES2, P1, P2: 0.8 × 0.8 × 0.8; Others: 0.6 × 0.6 × 0.6 0.375 × 0.375 × 1.0
Axial matrix size YS: 512 × 512 YS: 320 × 320 256 × 256 98 × 98 YS1, YS2, ES3, P1, P2: 240 × 256; Others: 256 × 320 512 × 512
Slice/partitions YS: 160 YS: 80 YS: 160; ES, P: 192 YS: 52; ES, P: 62 YS1, YS2, ES3, P1, P2: 176; Others: 320 72
Repetition time, ms YS: 3200 YS: 6.18 2300 YS: 6300; ES, P: 7100 6000 28
Echo time, ms YS: 402 YS: 2.75 YS: 2.98; ES, P: 2.03 84 YS: 2.64; ES: 2.05 20
Inversion time, ms / / 900 / 800/2700 /
Flip angles, degrees YS: 120 YS: 49 9 90 7/5 10
Target Whole Brain Thalamus Whole Brain Whole Brain Whole Brain Thalamus