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. 2019 Feb 4;9:1366. doi: 10.1038/s41598-018-37613-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Aggressive behaviour. Female Tph2 wildtype (WT) and knockout (KO) mice (focal animals) were housed together with a female of the same or the other genotype (partner animal), resulting in four combinations (focal animal/partner animal, n = 10 each): WT/WT, WT/KO, KO/WT and KO/KO. Behaviour was recorded on day 1 and day 5. Data are presented as boxplots with medians and 25–75% quartiles (box). The whiskers range from the minimum to the maximum of those observations with a distance from the box of less than 1.5 times the length of the box. Observations outside this area are represented as circles. Statistics: see Methods section; (a) chasing on day 1; (b) chasing on day 5; (c) escalated fighting on day 1; (d) escalated fighting on day 5.