Fig. 3. miR-29c-3p inhibits tumorigenicity of hepatocellular carcinoma (HCC) in vivo and activates Hippo signaling.

a MHCC-97H cells transfected with pre-miR-29c-3p were subcutaneously inoculated into nude mice to form tumor. b Tumor volume and weight growth curves were recorded. c HepG2 cells transfected with pre-miR-29c-3p were subcutaneously inoculated into nude mice to form tumors. d Tumor volume and weight growth curves were recorded. e Protein expression of Hippo signaling pathway components, including proliferation- and apoptosis-related indicators, after transfection with pre-miR-29c-3p in MHCC-97H cells. f Protein expression of Hippo signaling pathway components, including proliferation- and apoptosis-related indicators, after transfection with pre-miR-29c-3p in HepG2 cells; *p < 0.05, **p < 0.01, ***p < 0.001