Table 2.

Univariate and multivariate analysis of different prognostic variables and overall survival (OS) in HCC patients

Variables	n	Univariate analysis		Multivariate analysis model
		HR (95% CI)	P	HR (95% CI)	P
Sex		1.369 (0.843–1.695)	0.869
Female	58
Male	92
Age (year)		2.016 (0.860–1.961)	0.692
<50	82
≥50	68
AFP (ng/mL)		1.654 (0.598–1.693)	0.581
≤20	69
>20	81
HBsAg		2.463 (1.596–2.032)	0.439
Positive		94
Negative		56
Liver cirrhosis		0.961 (0.536–1.934)	0.506
Presence	85
Absence	65
TNM stage		0.933 (0.536–1.964)	0.783
I/II	91
III/IV	59
Tumor size (cm)		1.862 (1.639–2.533)	0.031	0.869 (1.036–2.695)	0.008
≤5	76
>5	74
Multiplicity		0.969 (0.569–1.965)	0.736
Single	71
Multiple (≥2)	79
Intrahepatic metastasis		0.693 (0.669–1.546)	0.963
Presence	85
Absence	65
Vascular invasion		1.236 (1.893–2.361)	0.901
Presence	74
Absence	76
miR-29c-3p expression		2.369 (1.069–2.465)	0.002	2.023 (1.530–3.039)	0.015
Low	95
High	55

HCC hepatocellular carcinoma, HR hazard rate, CI confidence interval, AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen,TNM tumor, node, metastasis

Bold values indicate statistical significance