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. 2019 Feb 4;9:1281. doi: 10.1038/s41598-019-39018-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tissue microarray analyses for IL13Rα2 expression. Multiple series of tissue microarrays were subjected to immunohistochemical analysis by using anti-IL13Rα2 antibody (KH7B9). Expression of IL13Rα2 was detected in the cytoplasm or membrane of melanoma cells (arrows). Red arrowheads indicate melanin pigment. (A) Benign naevus of the right face. (B) Metastatic malignant melanoma from the armpit (lymph node). (C) Malignant melanoma of the thigh. (D) Malignant melanoma of the cunnus. (E) Malignant melanoma of the skin. IL13Rα2 was expressed by melanoma cells (arrows) but not by stromal cells (S). (F) Malignant melanoma of the right sole. Scale bar: 50 μm (A), 20 μm (B–F).