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Best3 mRNA is expressed in the primary culture of mouse astrocytes. TG caused very small changes in total Best3 (A) and in its short splice variant expression (C), but induced a noticeable increase in expression of the long “+6” splice variant of Best3 (B). TG-treated cells showed a pronounced ER-stress (E) and increase in nestin expression (D). ∗∗P < 0.01, ∗∗∗P < 0.001 t-test control vs. treatment.
