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. 2019 Feb 4;9:1325. doi: 10.1038/s41598-018-37394-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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2D and 3D images of three different I2E-stained tumorous lungs. Tomograms of three tumorous lung samples (A–C) with their corresponding three-dimensional renderings (D–F) shown below, with normal lung tissue represented in transparent white to allow the visualization of the tumorous lesions pseudo-colored in pink. Pink regions in (D) correspond to 16.9 % of the total volume of this specimens, while this number is equal to 20.7 % in (E), and 65.8 % in (F). Scale bar: 1 mm.