Table 2.

Sequencing Alignments Summary. The total number of mapped microbial read-pairs was estimated using single aligned read-pairs as reported by Bowtie 2.0 before filtering by mapping quality (MAPQ).

Group	Mean High Quality Read Pairs	Mean Human Genome Pairsa	Mean Microbial Pairsb	Microbial Fraction (PPM)c
MS (N = 12)	7.19E + 07	2.73E + 07	8924 ± 1292	128.8 ± 21.3*
Control (N = 15)	8.17E + 07	3.78E + 07	6487 ± 1158	77.4 ± 10.3
OND (N = 3)	7.01E + 07	2.89E + 07	3925 ± 798	55.1 ± 3.5

^aConcordant read pairs mapping to either the human genome/transcriptome or the PhiX internal sequencing control.

^bConcordant read pairs mapping once to the panmicrobial database ± standard error of the mean (SEM).

^cMicrobial concordant read pairs divided by HQ Read Pairs, multiplied by 10⁶ ± SEM.

*P < 0.05 compared with the control group.