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. 2019 Feb 4;9:1302. doi: 10.1038/s41598-018-37690-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Echocardiographic results. (a) Representative M-mode images, (b) anterior wall thicknesses in systole (AWTs), (c) anterior wall thicknesses in diastole (AWTd), (d) septal wall thicknesses in systole (SWTs), (e) septal wall thicknesses in diastole (SWTd), (f) heart rate, (g) ejection fraction, (h) E/e′ ratio. White bars represent the sham-operated group, and grey bars represent the chronic kidney disease (CKD) group. Values are means ± SEM, n = 9–10, *p < 0.05 vs. sham within the same time point, ^#p < 0.05 vs. week -1. (Numeric p-values over the bars refer to the comparison between groups within the same time point)