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. 2019 Feb 4;9:1208. doi: 10.1038/s41598-018-37988-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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CcoA-like transporter (CalT) Protein Similarity Network. A protein similarity network of MFS members that are homologous to CcoA is shown. Each node (circle) represents one or more protein sequences, and each edge (solid line) represents similarity between two proteins (threshold set at an alignment score of 75). (A) Nodes are colored by taxonomic classes as indicated. The locations of nodes representing proteins examined in this study are indicated with blue arrows. (B) Nodes are colored by clusters as found in, and numbered according to Fig. 2A. Nodes that represent proteins encoded by genes found near a riboflavin biosynthetic pathway (RBP) cluster are colored red in the pop-out.