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. 2019 Feb 4;9:1175. doi: 10.1038/s41598-018-37602-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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SPCA2, Kv10.1, Orai1 and DDR1 tissue expression. DDR1, Kv10.1, Orai1 and SPCA2 expression in breast cancer tissues. (A) Representative immunohistochemical staining of DDR1, Kv10.1, Orai1 and SPCA2 in serial sections of breast tissue. 40x magnifications of tumor (bottom line) is compared to matched normal (up line) tissues. Immunohistochemistry shows the expression of the different proteins in the same area of the sections; staining is higher in tumor areas. (B) Comparison of staining scores for DDR1, Kv10.1, Orai1 and SPCA2 in non-tumor vs tumor areas (n = 29; ***p < 0,001, Student T test for paired samples).