Table 3.
PTSD and other psychiatric diagnosis in trauma exposed population by MFFA.
| PTSD diagnosis | Population percent exposed to trauma | N(%) with PTSD | PTSD odds ratio (95% CI) (unadjusted) | PTSD odds ratio (95% CI) model 1 | PTSD odds ratio (95% CI) model 2 | PTSD odds ratio (95% CI) Model 3A | PTSD odds ratio (95% CI) Model 3B | PTSD odds ratio (95% CI) Model 3C | |
| Neglect | 44.3 | 21 (10.3) | 2.21 (1.34–3.64) p = 0.002 | 2.17 (1.32–3.59) p = 0.002 | 2.09 (1.24–3.52) p = 0.005 | 1.80 (1.05–3.08) p = 0.03 | 1.75 (1.02–3.01) p = 0.04 | 1.60 (0.92–2.77) p = 0.1 | |
| Antipathy | 45.0 | 15 (14.3) | 3.15 (1.75–5.65) p < 0.001 | 2.86 (1.59–5.14) p < 0.001 | 2.80 (1.51–5.21) p = 0.001 | 2.25 (1.20–4.21) p = 0.01 | 2.18 (1.14–4.17) p = 0.02 | 2.01 (1.04–3.90) p = 0.04 | |
| Punishment | 65.5 | 19 (11.5) | 2.47 (1.47- 4.14) p < 0.001 | 2.67 (1.57–4.52) p < 0.001 | 2.63 (1.53–4.52) p < 0.001 | 2.01 (1.14–3.56) p = 0.02 | 2.06 (1.16–3.65) p = 0.01 | 2.28 (1.29–4.03) p = 0.005 | |
| Separation | 44.0 | 27 (6.6) | 1.27 (0.82–1.98) p = 0.3 | 1.28 (0.82–2.01) p = 0.3 | 1.28 (0.81–2.02) p = 0.3 | 1.19 (0.75–1.89) p = 0.5 | 1.09 (0.69–1.74) p = 0.7 | 1.13 (0.70–1.83) p = 0.6 | |
| Any MFFA | 43.5 | 57(8.5) | 2.66 (1.83–3.85) p < 0.001 | 2.49 (1.56–3.98) p < 0.001 | 2.67 (1.64–4.38) p < 0.001 | 2.46 (1.48–4.08) p = 0.001 | 2.01 (1.18–3.43) p = 0.01 | 2.22 (1.34–3.67) p = 0.002 |
|
| No of MFFA | |||||||||
| 1 | 41.3 | 36 (7.2) | 2.10 (1.38–3.20) p = 0.001 | 2.14 (1.28–3.56) p = 0.004 | 2.30 (1.35–3.92) p = 0.002 | 2.13 (1.23–3.69) p = 0.007 | 1.90 (1.06–3.40) p = 0.03 | 1.95 (1.12–3.37) p = 0.02 | |
| 2 | 49.8 | 13 (10.6) | 3.84 (2.07–7.12) p < 0.001 | 3.18 (1.45–7.01) p = 0.004 | 3.42 (1.50–7.80) p = 0.003 | 2.99 (1.28–6.97) p = 0.01 | 2.07 (0.85–5.02) p = 0.1 | 2.97 (1.29–6.86) p = 0.01 | |
| 3+ | 57.8 | 8 (18.6) | 8.26 (3.79–17.99) p < 0.001 | 7.16 (2.37–21.66) p < 0.001 | 6.94 (2.32–20.75) p = 0.001 | 6.64 (2.17–20.31) p = 0.001 | 3.16 (0.74–13.63) p = 0.12 | 3.36 (1.13–11.71) p = 0.03 | |
| Other DSM psychiatric diagnosis | Population percent exposed to trauma | N(%) with other DSM | Other DSM odds ratio (95% CI) (unadjusted) | Other DSM odds ratio (95% CI) model 1 | Other DSM odds ratio (95% CI) model 2 | Other DSM odds ratio (95% CI) Model 3A | Other DSM odds ratio (95% CI) Model 3B | Other DSM odds ratio (95% CI) Model 3C | |
| Neglect | 44.3 | 82 (40.4) | 2.15 (1.59–2.91) p < 0.001 | 2.07 (1.52–2.81) p < 0.001 | 1.81 (1.30–2.50) p < 0.001 | 1.67 (1.20–2.32) p = 0.002 | 1.65 (1.19–2.30) p = 0.003 | 1.67 (1.19–2.33) p = 0.003 | |
| Antipathy | 45.0 | 51 (48.1) | 2.88 (1.91–4.33) p < 0.001 | 2.66 (1.76- 4.01) p < 0.001 | 2.74 (1.79–4.20) p < 0.001 | 2.44 (1.60–3.72) p < 0.001 | 2.35 (1.53- 3.60) p < 0.001 | 2.39 (1.53–3.74) p < 0.001 | |
| Punishment | 65.5 | 60 (36.1) | 1.70 (1.22–2.39) p = 0.002 | 1.87 (1.34–2.63) p < 0.001 | 1.80 (1.26–2.55) p = 0.001 | 1.59 (1.12–2.27) p = 0.01 | 1.60 (1.12–2.30) p = 0.01 | 1.61 (1.11–2.35) p = 0.01 | |
| Separation | 44.0 | 118 (28.8) | 1.20 (0.94- 1.53) p = 0.1 | 1.23 (0.96–1.57) p = 0.1 | 1.17 (0.90–1.51) p = 0.2 | 1.14 (0.88–1.47) p = 0.3 | 1.09 (0.83–1.42) p = 0.5 | 1.16 (0.89–1.50) p = 0.3 | |
| Any MFFA | 43.5 | 194 (37.3) | 1.71 (1.48–1.98) p < 0.001 | 1.67 (1.39–2.01) p < 0.001 | 1.56 (1.28–1.89) p < 0.001 |
1.52 (1.25–1.85) p < 0.001 | 1.43 (1.18–1.74) p < 0.001 | 1.46 (1.20–1.78) p < 0.001 | |
| No of MFFA | |||||||||
| 1 | 41.3 | 130 (25.9) | 1.52 (1.30–1.79) p < 0.001 | 1.52 (1.24–1.86) p < 0.001 | 1.44 (1.17–1.78) p = 0.001 | 1.41 (1.14–1.75) p < 0.001 | 1.36 (1.09–1.69) p = 0.006 | 1.37 (1.11–1.70) p = 0.004 | |
| 2 | 49.8 | 40 (32.8) | 1.88 (1.38–2.56) p < 0.001 | 1.80 (1.24–2.62) p = 0.002 | 1.52 (1.02–2.28) p = 0.04 | 1.47 (0.98–2.20) p = 0.06 | 1.33 (0.89–1.98) p = 0.2 | 1.39 (0.92–2.12) p = 0.1 | |
| 3+ | 57.8 | 24 (54.5) | 5.64 (3.56–8.92) p < 0.001 | 5.33 (2.93–9.70) p < 0.001 | 5.00 (2.64–9.46) p < 0.001 | 4.81 (2.52–9.17) p < 0.001 | 4.00 (2.06–7.76) p < 0.001 | 4.28 (2.14–8.53) p < 0.001 |
Model 1 age, sex, ethnicity and twin status;
Model 2 model 1 variables plus deprivation, employment, marital status, years of education and urbanicity;
Model 3A includes model 1 and 2 variables plus high risk events (interpersonal violence); Model 3B includes model 1 and 2 variables plus cumulative trauma;Model 3C includes model 1 and 2 variables plus psychiatric diagnoses (for analyses where PTSD is dependent variable) or PTSD (for analysis where psychiatric diagnosis was dependent variable).