Table 2.
Accumulative excretion (% dose) of naringin, naringenin, and total in urine and feces after a single oral administration of 42 mg/kg naringin to aged rats.
| Accumulative excretion (% dose) | Male + female | Male | Female a |
|---|---|---|---|
| Urine | |||
| Naringin | 4.9E-03 ± 2.1E-03 | 2.5E-03 ± 5.9E-04 | 7.2E-03 ± 4.0E-03 |
| Naringenin | 19.0 ± 2.9 | 12.7 ± 2.6 | 25.3 ± 3.6* |
| Urinary total | 93.4 ± 9.4 | 84.9 ± 16.9 | 101.9 ± 8.7 |
| Feces | |||
| Naringin | 1.7E-03 ± 7.8E-04 | 6.4E-04 ± 4.2E-04 | 2.7E-03 ± 1.2E-03 |
| Naringenin | 3.7E-04 ± 7.5E-05 | 2.7E-04 ± 1.1E-04 | 4.5E-04 ± 9.6E-05 |
| Fecal total | 4.7 ± 3.9 | 0.7 ± 0.3 | 8.8 ± 7.7 |
aCompared with male aged rats. ∗P < 0.05.