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. 2018 Dec 20;28(2):145–156. doi: 10.1177/0963689718819443

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 6. — (A) Claudin-1 protein expression was slightly increased with C+P as compared with stroke groups without treatment at 6 and 24 h after reperfusion. (B) A significant decrease in claudin-5 protein expression was seen after stroke, and this decrease was reversed by C+P± temperature control at 6 (^##p<0.01) and 24 h (^#p<0.05). Occludin protein expression (C) and ZO-1 protein expression (D) were increased by C+P without temperature control but not with temperature control as compared with stroke groups without treatment at 6 (slightly) and 24 h (significantly, ^#p<0.05) after reperfusion. (E) Laminin protein expression was increased by C+P with or without temperature control compared to stroke groups at 6 (slightly) and 24 h (significantly, ^#p<0.05) after reperfusion. Representative immunoblots are presented.