Unilateral ureteral obstruction (UUO) kidneys treated with hepatocyte growth factor transgenic (HGF-tg) mesothelial cell (MC) sheets retained their parenchyma for 28 days. (A) Representative photographs of a whole kidney (upper), transaxial cross-section (lower left), and parenchyma (lower right; corresponding to the boxed area) on day 28 after UUO using specimens obtained from the no sheet (left panel), MC sheet (center panel), and HGF-tg MC sheet (right panel) groups. The areas between the yellow arrows indicate the thickness of the parenchyma. Scale bars, 10 mm in upper panels; 2 mm in lower panels. (B) Renal parenchyma thickness (left panel) and renal pelvis longitudinal (center panel) and horizontal (right panel) lengths of the kidney at 28 days after UUO in the no sheet, MC sheet, and HGF-tg MC sheet groups. *P<0.01 (n=5 for all groups).