Table 1.
Evidence-based rating system used in this review
Category Definition | |
---|---|
Strength of the Recommendation | |
A | Should always be offered. |
B | Should generally be offered. |
C | Evidence for efficacy is insufficient to support a recommendation for or against, or evidence for efficacy might not outweigh adverse consequences, or cost of the approach. Optional. |
D | Moderate evidence for lack of efficacy or for adverse outcome supports a recommendation against use. Should generally not be offered. |
E | Good evidence for lack of efficacy or for adverse outcome supports a recommendation against use. Should never be offered. |
Quality of Evidence Supporting the Recommendation | |
I | Evidence from at least one properly randomized, controlled trial. |
II | Evidence for at least one well-designed clinical trial without randomization, from cohort or case-controlled analytic studies (preferable from more than one center) or from multiple time-series or dramatic results from uncontrolled experiments. |
III | Evidence from opinions of respected authorities based on clinical experience, descriptive. |