. Author manuscript; available in PMC: 2020 Feb 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2018 Nov 24;25(2):e46–e54. doi: 10.1016/j.bbmt.2018.11.021

Table 3.

Evaluation measures of ocular GVHD

	Recommendation level
Measure	Diagnosis	Response measure
Hematologist assessment
NIH eye score	A-II³⁷	A-II³⁹
Schirmer test without anesthesia	A-II^{20, 34-36}	D-II^{38, 39}
Ocular surface disease index (OSDI)	B-II³⁵	B-II³⁹
Lee eye subscale	B-II³⁷	B-II^{37, 39}
Patient-reported global rating of eye symptoms (0-10)	B-II³⁷	B-II³⁹
Ophthalmologist assessment
Corneal staining	A-II^{35, 37}	B-II^*³⁷
Tear film breakup time (TBUT)	B-II^{35, 37}	B-III
ICOGCG score	B-II^{35, 54}	C-III
Meibomian score^†	B-II³⁷	C-III
Lip-parallel conjunctival folds (LIPCOF)	C-II⁴⁷	C-III

Oxford grand total score.

^†

Meibomian glands plugging: 0 = none; 1 = 1-2 glands; 2 = 2-3 glands; 3 = all 5 glands, lid margin swelling.³⁷