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. 2018 May 18;103(2):181–185. doi: 10.1136/bjophthalmol-2017-311710

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Mean shape changes of the total (A) and posterior (B) cornea shown in the average of difference map in eyes that underwent a 2.4 mm nasal clear corneal incision (CCI; nasal CCI group) and eyes that underwent a 2.4 mm temporal CCI (temporal CCI group). (A) For the total cornea, wedge-shaped flattening and coupled steepening were observed around the CCIs in the early postoperative periods in both groups, and these changes diminished over time. These changes were more prominent and extended closer to the central cornea in the nasal CCI group than in the temporal CCI group until 4 weeks. At 8 weeks postoperatively, slight coupled steepening was observed in the temporal CCI group, while slight peripheral flattening and coupled steepening were observed in the nasal CCI group; the difference between groups became slight by 8 weeks postoperatively. (B) A focal steepening occurred around both the nasal and temporal CCIs at 2 days after surgery, and this steepening was slightly greater in the nasal CCI group than in the temporal CCI group. This wound-related steepening rapidly diminished and was not detected at 4 weeks after surgery or later in either group.