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. 2019 Jan 29;10:3. doi: 10.3389/fphar.2019.00003

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Copyright © 2019 Kunzelmann, Ousingsawat, Cabrita, Doušová, Bähr, Janda, Schreiber and Benedetto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular and functional relationship of CFTR, SLC26A9 and TMEM16A. Both SLC26A9 and TMEM16A interact with CFTR via their C-terminal PDZ (PSD-95/Discs-large/ZO1) -binding domains with the help of the PDZ-protein NHERF1 (Na⁺/H⁺ exchanger regulatory factor 1).