Table 1.
Demographic and clinic characteristics of the cohort of women with PaHIV (total=119)
| Pregnant* (total=17) | Whole cohort (total=119) | |
|---|---|---|
| Median age (years) (IQR) | 25 (23–28) | 20 (18–24) |
| Mean BMI (kg/m2) | 21.74 | 24.18 |
| Underweight (BMI <18.5 kg/m2) (n) | 1 (6%) | 4/93 (4%) |
| Overweight (BMI >25 kg/m2) (n) | 1 (6%) | 30/93 (32%) |
| Black or mixed ethnicity (n) | 15 (88%) | 100/119 (84%) |
| Median CD4 cell count at time of audit (cells/mm3) (IQR) | 539 (285–737) | 666 (479–853) |
| Median CD4 cell count at time of pregnancy (cells/mm3) (IQR) | 439 (213–690) | – |
| Median nadir CD4 (cells/mm3) (IQR) | 256 (70–390) | 320 (148–479) |
| Undetectable VL <50 copies/mL at time of audit (n) | 10 (59%) | 93 (78%) |
| Individuals using alcohol (n) | 8/14 (57%) | 49/109 (45%) |
| Individuals smoking (n) | 10 (59%) | 26/113 (23%) |
| Median years ART exposure (IQR) | 12 (9–15) | 13 (9–17) |
| Exposed ever to AZT, ddI or d4T (n) | 8 (47%) | 50/95 (53%) |
| Previous AIDS-defining diagnosis (n) | 6 (35%) | 42/110 (38%) |
AZT: zidovudine; BMI: body mass index; ddI: didanosine; d4T: stavudine; PaHIV: perinatally acquired HIV; VL: viral load.
*There were 26 pregnancies and 20 live births. All infants had tested HIV negative to date. Three women had been seen by fertility services prior to conception.