Table 4.
Changes in total HIV-1 DNA
| 50 mg ABX464
(n=2) |
150 mg ABX464
(n=14) |
Pooled ABX464 arms
(n=16) |
Placebo
(n=4) |
||
|---|---|---|---|---|---|
| Day 0 (copies/million PBMCs) | Mean (SD)
Median [range] |
300.0 (21.2)
300.0 [285–315] |
444.6 (289.5)
393.0 [72–961] |
426.6 (274.1)
352.5 [72–961] |
183.0 (85.4)
163.5 [112–293] |
| Day 28 (copies/million PBMCs) | Mean (SD)
Median [range] |
185.0 (22.6)
185.0 [169–201] |
398.9 (226.6)
388.5 [77–734] |
372.1 (223.3)
325.0 [77–734] |
241.3 (204.2)
188.5 [77–511] |
| Change between day 0 and day 28 (copies/million PBMCs) | Mean (SD)
Median [range] |
-115.00 (1.41)
-115.00 [-116.0–114.0] |
-45.79 (181.75)
-40.00 [-434.0–194.0] |
-54.44 (170.84)
-84.50 [-434.0–194.0] |
58.25 (118.99)
25.00 [-35.0–218.0] |
n: number of participants; SD: standard deviation.