Table 2.
Diagnostic performance of SERS: sensitivity, specificity, PPV, and NPV of cyst fluid Hp determined by rapid SERS assay in the differential diagnosis of benign and malignant epithelial ovarian tumors
| Performance | SERS | ||
|---|---|---|---|
| Disease | |||
| Test | CA | Non-CA | Total |
| Positive | 51 | 5 | 56 |
| Negative | 3 | 52 | 55 |
| Total | 54 | 57 | 111 |
| 95% CI | |||
| Lower | Upper | ||
| Sensitivity | 94.40% | 83.60% | 98.60% |
| Specificity | 91.20% | 80% | 96.70% |
| PPV | 91.10% | 79.60% | 96.70% |
| NPV | 94.50% | 83.90% | 98.60% |
Abbreviations: CA, cancer; NPV, negative predictive value; PPV, positive predictive value; SERS, surface-enhanced Raman spectroscopy.