Table 1.

FRAX and garvan fracture risk calculator.

Characteristic	Garvan model	FRAX model
Risk factors considered	Sex Age No. of prior fractures No. of falls over the past 12 months Femoral neck BMD	Sex Age Prior fracture (yes/no) Body weight Body height Femoral neck BMD Parental history of fracture Current smoking Alcohol (3 or more units/day) Chronic corticosteroid use Rheumatoid arthritis Secondary osteoporosis
Method for selecting variables	Bayesian Model Averaging method	NA
Adjustment for competing risk of mortality	No	Yes
Statistical model	Cox proportional hazards	NA
Output	5- and 10-year risk of total fracture 5- and 10-year risk of hip fracture	10-year risk of major fracture 10-year risk of hip fracture
Typical AUC, median (range)
Total fracture (in validation studies)	0.74 (0.64–0.88)	0.69 (0.54–0.83)
Hip fracture (in validation studies)	0.79 (0.67–0.85)	0.78 (0.70–0.88)
Website	Garvan.org.org/bone-fracture-risk	shef.ac.uk/FRAX

BMD, bone mineral density; NA, not available; AUC, area under the receiver operating characteristic curve.

Data were derived from Nguyen and Eisman. J Clin Densitom 2017;20:368–78 [53].

FRAX (Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK), Garvan Fracture Risk Calculator (Garvan Institute of Medical Research, Sydney, Australia).