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. 2019 Jan 31;14:913–920. doi: 10.2147/IJN.S190164

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© 2019 Li et al. This work is published and licensed by Dove Medical Press Limited

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In vitro cytotoxicity of RPV-LPNs, E-LPNs, and RPV solution evaluated by assaying the BALB/c-3T3 fibroblast viability.

Notes: Data represent mean ± SD, N=6. *P<0.05. Various doses of RPV-LPNs, E-LPNs, and RPV solution were added to the 48-well plate incubating cells. The amount of MTT converted to formazan was measured to determine the percentage of viable cells, using a microplate reader at a wavelength of measured at 570 nm.

Abbreviations: RPV, ropivacaine; LPNs, lipid-polymer hybrid nanoparticles.