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. 2019 Jan 18;9:1531. doi: 10.3389/fphar.2018.01531

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Copyright © 2019 Shou, Jin, Lang, Shan, Ni, Cheng, Li, Fu and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The enrichment analysis of candidate genes of paeoniflorin on allergic asthma model mouse. (A) Heatmap classifying the candidate genes of paeoniflorin on allergic asthma model mouse. (B) mRNA expression level of Ttl, Dusp, Map3k7 and Asah1f was detected by real-time PCR assay. (C) The genes were mainly related to such biological functions: fatty acid metabolism, inflammation response, cytokinesis, chromosome and adhesion plaque. The data were expressed as the mean ± SD. ^∗Means control group vs model group (^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001); ^#Means model group vs paeoniflorin group (^#p < 0.05, ^##p < 0.01, and ^###p < 0.001).