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The mesenteric lymph node of a male rhesus macaque collected at day 22 following irradiation at 11 Gy has a large number of MxA+ (activated) immunocytes in the medulla (m), with a smaller number in the hypocellular cortex (c). Note the accumulation of activated immunocytes in the subcapsular sinus (arrow), indicating activated cells are arriving from peripheral tissues. MxA IHC stain, 5x objective magnification.
