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. 2019 Jan 18;10(6):673–683. doi: 10.18632/oncotarget.26586

Figure 2. miR-194-5p modulates sensitivity to paclitaxel in ovarian cancer cell lines.

Figure 2

(A) miRNA qRT-PCR. Cells were transfected with pre-miR-194-5p (miR-194-5p) or control miR (miR-ctrl). Twenty-four hours later, expression of miR-194-5p relative to RNU6B expression was calculated using the 2-ΔΔCT method. Relative fold differences are presented. (B) MTS assay. Twenty-four hours after transfection with miR-194-5p or control miR-ctrl, cells were treated with paclitaxel for 72 hours and cell viability was assessed. Cell viability is shown relative to that in paclitaxel-free conditions. (C) miRNA qRT-PCR. Cells were transfected with anti-miR-194-5p or miR-ctrl for 24 hours. (D) MTS assay. As described in B, cells were transfected with anti-miR-194 or miR-ctrl and cell viability was assessed. Experiments were performed in triplicate. Data are represented as mean ± SE and are obtained from three independent experiments. *P < 0.05; **P < 0.01.