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. 2018 Jun 25;12(6):538–547. doi: 10.1080/19336918.2018.1477901

Figure 3.

Figure 3.

Targeted inhibition of ERRα suppressed migration and invasion of EC cells. (A) HEC1A and ECC cells were transfected with si-NC or si-ERRα for 24 h; (B) After transfected with si-NC or si-ERRα for 48 h, the expression of MMP-2/-9 in HEC1A and ECC cells were checked by western blotting; (C) The wound healing assay for HEC1A and ECC cells transfected with si-NC or si-ERRα for 48 h; (D) The in vitro invasion assay of HEC1A and ECC cells transfected with si-NC or si-ERRα for 48 h; (E) HEC1A and ECC cells were treated with or without XCT-790 (1 µM) for 48 h, the expression of MMP-2/-9 in HEC1A and ECC cells were checked by western blotting; (F) The in vitro invasion assay of HEC1A and ECC cells treated with or without XCT-790 (1 µM) for 48 h. Each experiment has been replicated for three times. * p<0.05, **p<0.01 as compared with the control group.