Table 2.
Analysis of the double exponential fit to the dwell time distribution for BBP on WT RNA using nonlinear least squares fitting of histogram bin centers.
| No. of Bins | Bin Size | Parameter | Non Linear Least Square Fit | Confidence Intervals | R2/Adj R2 | Corresponding Figure | |||
|---|---|---|---|---|---|---|---|---|---|
| 68% | 95% | ||||||||
| 6 | Equal | a1 | 0.91 | −1.32 | 3.14 | −5.06 | 6.88 | 0.9465/0.9108 | 3A |
| τ1(s) | 38.5 | −29.2 | 106.1 | −142.6 | 219.5 | ||||
| τ2(s) | 116.1 | −2399 | 2631 | −6617 | 6849 | ||||
| 6 | Variable | a1 | 0.82 | 0.74 | 0.91 | 0.59 | 1.06 | 0.9996/0.9994 | 3B |
| τ1(s) | 15.4 | 13.5 | 17.2 | 10.4 | 20.3 | ||||
| τ2(s) | 104.9 | 22.1 | 188.0 | −116.7 | 326.5 | ||||
| 9 | Variable | a1 | 0.70 | 0.65 | 0.75 | 0.59 | 0.81 | 0.9992/0.9989 | 3C |
| τ1(s) | 12.4 | 11.6 | 13.2 | 10.6 | 14.2 | ||||
| τ2(s) | 107.4 | 69.3 | 145.5 | 21.4 | 193.5 | ||||