Table 5. Differentially expressed milk candidate genes in mammary epithelial cells for milk quality and yield traits between different stages of lactation in Kashmiri and Jersey1.
| Genes | Kashmiri cattle (Log2Fold change) | Jersey (Log2Fold change) | ||||
|---|---|---|---|---|---|---|
| D15 vs D90 | D90 vs D250 | D15 vs D250 | D15 vs D90 | D90 vs D250 | D15 vs D250 | |
| LPL | -2.724 | 0.842 | -1.881 | 0.028 | -0.268 | -0.24 |
| GPAM | -3.258 | 1.993 | -1.264 | -3.694 | 3.73 | 0.035 |
| VLDLR | -1.825 | 1.999 | 0.174 | 0.506 | 0.64 | 1.147 |
| DGAT1 | 0.16 | -1.014 | -0.853 | -0.184 | 0.473 | 0.289 |
| ABCA1 | 1.477 | 2.015 | 3.492 | 1.168 | -0.424 | 0.744 |
| LPIN1 | -3.204 | 1.287 | -1.917 | 0.05 | 0.906 | 0.957 |
| ABCG2 | -2.178 | 1.251 | -0.927 | -3.76 | 3.929 | 0.16 |
| INSIG1 | -0.036 | -0.301 | -0.337 | 0.858 | 0.255 | 1.114 |
| ACSS1 | -1.258 | -0.238 | -1.496 | -2.283 | 0.095 | -2.187 |
| INSIG2 | 0.505 | 0.111 | 0.617 | 1.565 | -0.344 | 1.22 |
| ACSS2 | -1.859 | 1.834 | -0.024 | -2.762 | 2.558 | -0.211 |
| SCAP | 0.211 | -1.124 | -0.913 | -0.967 | -0.727 | -1.694 |
| ACSL1 | -1.035 | 1.346 | 0.311 | 0.521 | 0.333 | 0.854 |
| SREBF1 | -1.441 | -0.346 | -1.788 | -1.085 | 0.529 | -0.556 |
| SREBF2 | 0.607 | -0.849 | -0.241 | 0.242 | 0.224 | 0.466 |
| FABP3 | -2.29 | 1.638 | -0.652 | -3.9 | 3.218 | -0.682 |
| THRSP | -1.005 | 1.792 | 0.786 | -3.396 | 3.451 | 0.055 |
| PPARG | 4.542 | 0.55 | 5.092 | 1.01 | -0.738 | 0.272 |
| ACACA | -3.482 | 2.24 | -1.241 | -3.72 | 2.546 | -1.173 |
| PPARGC1A | 0.543 | 2.242 | 2.785 | -2.58 | 3.503 | 0.922 |
| FADS1 | -0.808 | 0.725 | -0.082 | 1.83 | -0.525 | 1.305 |
| PPARGC1B | 1.585 | 0.307 | 1.893 | -0.035 | 0.546 | 0.51 |
| FADS2 | 0.521 | 0.4 | 0.922 | 2.094 | -1.832 | 0.262 |
| FASN | -2.541 | 2.166 | -0.374 | -4.247 | 4.523 | 0.275 |
| SPTLC1 | -0.243 | 0.862 | 0.619 | 1.159 | 0.753 | 1.912 |
| SPTLC2 | 0.739 | 0.06 | 0.8 | 0.688 | 0.024 | 0.712 |
| SPHK2 | -1.347 | 0.817 | -0.529 | -1.157 | 0.224 | -0.933 |
| XDH | -2.595 | 2.311 | -0.284 | -1.451 | 2.262 | 0.811 |
| SGPL1 | 1.392 | 0.512 | 1.905 | 1.32 | -0.271 | 1.048 |
| UGCG | 0.862 | 0.809 | 1.671 | 1.293 | 2.355 | 3.649 |
| OSBP | -0.142 | -0.785 | -0.927 | -0.523 | 0.022 | -0.501 |
| BDH1 | -3.248 | 1.839 | -1.408 | -5.85 | 3.008 | -2.842 |
| OSBPL2 | -1.212 | 0.174 | -1.038 | -0.11 | 0.401 | 0.29 |
| OXCT1 | 0.161 | 0.757 | 0.919 | 0.756 | 0.223 | 0.98 |
| CSN1S1 | -0.238 | 0.598 | 0.36 | -0.07 | 0.581 | 0.511 |
| CSN1S2 | 0.33 | 0.485 | 0.815 | 0.15 | 0.124 | 0.275 |
| CSN3 | -0.021 | 0.27 | 0.248 | -0.268 | 0.617 | 0.349 |
| CSN2 | -0.189 | 0.295 | 0.106 | -0.283 | 0.293 | 0.009 |
| LGB | -0.588 | 0.5956 | 0.007 | 0.957 | 0.698 | 1.656 |
| LALBA | 0.148 | 0.48 | 0.629 | -0.037 | 0.173 | 0.135 |
| HK2 | 0.355 | 1.232 | 1.587 | -1.157 | 0.224 | -0.933 |
| SLC2A1 | -1.006 | 0.456 | -0.549 | 0.995 | 0.44 | 1.435 |
| SLC2A4 | 1.655 | 0.48 | 2.136 | -1.311 | -0.377 | -1.688 |
| SLC2A8 | -0.986 | 0.101 | -0.884 | -1.506 | -0.902 | -2.408 |
1Mammary epithelia cells were isolated from milk obtained from Kashmiri (n = 3) and Jersey (n = 3) cows at D15 (early lactation), D90 (mid-lactation) and D250 (late-lactation) and subjected to RNA-sequencing.