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. 2019 Feb 4;151(2):100–117. doi: 10.1085/jgp.201812138

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© 2019 Strange et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 2. — Examples of VRAC single-channel currents in a C6 glioma cell. Top panel shows membrane voltage. Middle panel shows voltage-dependent inactivation of whole-cell current induced by stepping membrane voltage from −80 to 120 mV. Bottom panel shows voltage-dependent current inactivation in an outside-out membrane patch stepped from a membrane voltage of −80 to 120 mV. Arrows show closing of single VRAC channels. Figure is modified from Jackson and Strange (1995b).