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. 2019 Feb 4;216(2):450–465. doi: 10.1084/jem.20180742

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© 2019 Ruiz et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 8. — Combination treatment with cisplatin and TAK1 inhibitor increases survival even with advanced tumors. (A) Scheme depicting experimental design for end-stage survival analysis of control, cisplatin-treated, and combination-treated KF mice. IT, intratracheal. (B) Kaplan-Meier curve showing effect of cisplatin (CPPD; 3.5 mg/kg) or cisplatin plus 5Z-7-oxozeaenol (7 mg/kg) treatment on survival of tumor-bearing KF mice (n = 4 vehicle and cisplatin, n = 6 combination). P value calculated using log-rank (Mantel–Cox) test (**, P = 0.0011). See also Fig. S5.