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. 2019 Feb 4;216(2):407–418. doi: 10.1084/jem.20181353

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© 2018 Rodriguez-Laguna et al.

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Figure 5. — Prox1-CreER^T2;LSL-Pik3ca^H1047R mice have lymphatics in their bones. (A and B) Representative images of femurs stained with an anti-podoplanin antibody. Femurs from Prox1CreER^T2;LSL-Pik3ca^H1047R mice (four out of nine mice), but not from LSL-Pik3ca^H1047R mice, had lymphatics. (C and D) Representative x-ray images of femurs from LSL-Pik3ca^H1047R and Prox1-CreER^T2;LSL-Pik3ca^H1047R mice. Femurs from LSL-Pik3ca^H1047R and Prox1-CreER^T2;LSL-Pik3ca^H1047R mice appear similar to one another. Bar, 50 µm.