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. 2019 Feb 4;216(2):253–266. doi: 10.1084/jem.20181965

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© 2018 Zheng and Cantley

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Figure 1. — Folate chemistry. (A) Chemical structure of THF. (B) Redox reactions for the pteridine ring of folates. (C) The 1C unit is derived from donors such as serine, exists in three different oxidation states, and is used for various biochemical processes.