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. 2019 Feb 4;218(2):422–432. doi: 10.1083/jcb.201803003

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© 2019 Byrum et al.

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Figure 5. — TPX2/Aurora A regulate DSB repair and replication fork stability via negative regulation of 53BP1. (A) Model of TPX2/Aurora A regulation of 53BP1 in response to double-strand breaks. (B) Model of TPX2/Aurora A function in response to replication stress. See text for details.