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Regulation of Cdk1 and PP2A-B55 activity. A schematic of how the mitotic kinases and mitotic phosphatases antagonize each other during mitosis. Upon activation of APC/C-Cdc20, the activity of Cdk1 drops and results in activation of PP2A-B55 and mitotic exit. Arrows indicate stimulation of activity while lines with perpendicular lines indicate inhibition.
