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. 2019 Jan 30;14:875–888. doi: 10.2147/IJN.S186225

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© 2019 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of DATS-MIONs.

Notes: (A) TEM imaging of a single nanoparticle. The scale bar is shown in the lower left corner. (B) Size distribution of DATS-MIONs. (C) Drug loading experiment. One gram of MIONs was used, and the weight of the loaded nanoparticles is shown. (D) Time course of H₂S release by DATS-MIONs at different nanoparticle concentrations measured on an H₂S-selective microelectrode. (E) Proliferation of HUVECs incubated with different concentrations of DATS-MIONs as monitored on a real-time cell analyzer.

Abbreviations: DATS, diallyl trisulfide; HUVECs, human umbilical vein endothelial cells; MIONs, mesoporous iron oxide nanoparticles; TEM, transmission electron microscopy.