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| Agent | Dose | Frequency | Duration |
|---|---|---|---|
| tPA | 10 mg | Twice daily | 3 d |
| DNase | 5 mg | Twice daily | 3 d |
Abbreviation: tPA, tissue plasminogen activator.
Source: Intrapleural use of tissue plasminogen activator and DNase in pleural infection. The New England Journal of Medicine 2011. 40
