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Comparison of FISH test and cytology in the diagnosis of all bladder transitional cell cancer (n = 3 959).
| FISH test | Cytology | p value | |
|---|---|---|---|
| True positive, n | 3 011 | 1 217 | |
| False positive, n | 54 | 20 | |
| True negative, n | 265 | 299 | |
| False negative, n | 629 | 2423 | |
| Sensitivity (%) | 82.7 | 33.4 | <0.001 |
| Specificity (%) | 83.1 | 93.7 | <0.001 |
| AUC | 0.829 | 0.636 | <0.001 |
| Positive predictive value (%) | 98.2 | 98.4 | |
| Negative predictive value (%) | 29.6 | 11.0 |
AUC, area under curve; FISH, fluorescence in situ hybridization.
