Table 1.
Correlation coefficients for the relationships between levels of circulating anti-Hsp60, anti-Hsp70, and anti-Hsp90 IgG, IgM, and IgA autoantibodies and selected parameters of RA patients including disease activity (DAS 28), Steinbrocker radiographic criteria (RTG), rheumatoid factor (RF), and serum cytokine levels. P values ≤ 0.05 were considered significant
| DAS 28 | RTG | RF | IFN-ɣ | TNF-α | IL-4 | |
|---|---|---|---|---|---|---|
| IgG | ||||||
| Anti-Hsp60 | − 0.081 | 0.339 | 0.267 | 0.253 | 0.117 | 0.328 |
| P = 0.622 | P = 0.058 | P = 0.188 | P = 0.121 | P = 0.479 | P = 0.042 | |
| Anti-Hsp70 | − 0.004 | − 0.220 | − 0.111 | 0.113 | − 0.022 | − 0.005 |
| P = 0.982 | P = 0.226 | P = 0.590 | P = 0.493 | P = 0.896 | P = 0.977 | |
| Anti-Hsp90 | − 0.277 | − 0.249 | − 0.085 | 0.372 | 0.183 | 0.147 |
| P = 0.088 | P = 0.169 | P = 0.681 | P = 0.020 | P = 0.264 | P = 0.373 | |
| IgM | ||||||
| Anti-Hsp60 | 0.179 | 0.093 | 0.199 | − 0.073 | − 0.161 | − 0.290 |
| P = 0.297 | P = 0.633 | P = 0.363 | P = 0.673 | P = 0.349 | P = 0.086 | |
| Anti-Hsp70 | 0.142 | 0.047 | 0.121 | − 0.213 | − 0.353 | − 0.273 |
| P = 0.409 | P = 0.809 | P = 0.582 | P = 0.212 | P = 0.035 | P = 0.107 | |
| Anti-Hsp90 | − 0.076 | − 0.046 | 0.087 | 0.006 | − 0.184 | − 0.307 |
| P = 0.660 | P = 0.811 | P = 0.694 | P = 0.971 | P = 0.282 | P = 0.068 | |
| IgA | ||||||
| Anti-Hsp60 | 0.050 | 0.245 | 0.390 | 0.014 | − 0.049 | 0.175 |
| P = 0.785 | P = 0.210 | P = 0.089 | P = 0.971 | P = 0.790 | P = 0.339 | |
| Anti-Hsp70 | 0.102 | 0.182 | 0.390 | − 0.156 | − 0.075 | − 0.018 |
| P = 0.579 | P = 0.353 | P = 0.089 | P = 0.394 | P = 0.685 | P = 0.921 | |
| Anti-Hsp90 | 0.047 | 0.248 | 0.477 | − 0.095 | − 0.035 | − 0.037 |
| P = 0.796 | P = 0.203 | P = 0.033 | P = 0.603 | P = 0.850 | P = 0.840 | |