Skip to main content
. 2019 Jan 30;10:21. doi: 10.3389/fgene.2019.00021

FIGURE 2.

FIGURE 2

IFT27 gene and protein. (A) Schematic of the IFT27 locus and (B) IFT27 protein and the position and/or nature of known mutations. Nomenclature is given according to the following RefSeq identifiers: NM_006860.4 and NP_006851.1. (C) Multiple sequence alignment of IFT27 proteins from different species and of the human RAB8a and RAB10 proteins. The secondary structures derived from the IFT27 structure are shown in black above the sequences (Bhogaraju et al., 2011). The mutation Tyr35 is highlighted using a black “∗” and the Switch I region is shown using a black line below the sequences. Residues are presented and colored according to the Jalview program (Waterhouse et al., 2009). Hs, Homo sapiens; Mm, Mus musculus; Xl, Xenopus laevis; Dr, Danio rerio; Cr, Chlamydomonas reinhardtii.