Table 1.
Study characteristics.
| Author (year) | Diagnostic criteria | Insomnia duration | Assessment | Comorbidity | N insomnia | N controls | %Female insomnia | % Female controls | Age insomnia (M) | Age controls (M) | Pharmaco intake | Caffeine intake | Alcol intake | Time of testing |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Altena et al., 2008 | RDC, Lichstein criteria | >2.5 years | Questionnaire | Subclinical psychiatric symptoms | 21 | 12 | 80.9 | 75 | 61 | 60 | Excluded | n/a | n/a | PM |
| Backhaus et al., 2006 | DMS-IV | 9.2 years | Clinical interview | Excluded | 15 | 13 | 50 | 61.3 | 41.6 | 40.1 | Excluded | n/a | n/a | AM |
| Bonnet and Arand, 1995 | SOL>45 or WASO>60 min, 4 nights per week for 1 year | 8 years | Questionnaire | Excluded | 10 | 10 | n/a | n/a | 38.3 | 38.6 | Excluded | Excluded | n/a | Repeated testing |
| Cellini et al., 2014 | RDC | n/a | Clinical interview, questionnaire | Excluded | 13 | 13 | 61.5 | 46.1 | 23.3 | 24.3 | Excluded | Excluded | Excluded | PM |
| Chen et al., 2016 | ICSD-3 | >6 months | Questionnaire | Excluded | 21 | 20 | 71.4 | 65 | 41.8 | 38.1 | n/a | n/a | n/a | AM |
| Covassin et al., 2011 | DSM-IV | n/a | Clinical interview, questionnaire | Excluded | 8 | 8 | 50 | 50 | 22.9 | 24.8 | Excluded | Excluded | Excluded | Repeated testing |
| Crenshaw and Edinger, 1999 | DMS-III-R | n/a | Clinical interview | Excluded | 32 | 32 | 50 | 50 | 67.7 | 67.5 | Excluded | n/a | n/a | Repeated testing |
| Edinger et al., 2000 | DMS-III-R | >6 months | Clinical interview | Excluded | 27 | 31 | 44.4 | 51.6 | 49.7 | 46.4 | Excluded | n/a | n/a | Repeated testing |
| Edinger et al., 2008 | DSM-IV | n/a | Clinical interview | Excluded | 79 | 84 | 54.4 | 48.8 | 50 | 48.6 | Excluded | n/a | n/a | Repeated testing |
| Fang et al., 2008 | DSM-IV | n/a | Questionnaire, actigraphy | Excluded | 18 | 21 | 66.7 | 66.7 | 34.1 | 27.8 | n/a | Excluded | Excluded | PM |
| Fortier-Brochu and Morin, 2014 | DSM-IV, ICD-10 | 17.3 years | Clinical interview, diary | Excluded | 25 | 16 | 56 | 50 | 44.4 | 42.8 | Excluded | Excluded | Excluded | AM |
| Guo et al., 2017 | DSM-IV | n/a | Questionnaire | Excluded | 40 | 48 | 77.5 | 72.9 | 37.3 | 39.8 | Excluded** | n/a | n/a | n/a |
| Haimov et al., 2008 | Lichstein criteria | n/a | Questionnaire, actigraphy | Excluded | 35 | 64 | 57.1 | 67.2 | 73.6 | 71.6 | Excluded | n/a | n/a | PM |
| Joo et al., 2013 | ICSD-2 | >1 year | Clinical interview, diary, questionnaire | Excluded | 27 | 27 | 92.5 | 85 | 52.3 | 51.7 | Excluded | Excluded | Excluded | n/a |
| Khassawneh et al., 2018 | DSM-5, ICSD-3 | n/a | Clinical interview, questionnaire, psg | Excluded | 35 | 54 | 71.4 | 70.4 | 40.6 | 31.5 | Excluded | n/a | n/a | Repeated testing |
| Liu et al., 2014 | DSM-IV | 6.4 years | Clinical interview, questionnaire | Excluded | 36 | 26 | 58.3 | 61.5 | 42.9 | 40.5 | Excluded | Excluded | Excluded | n/a |
| Lovato et al., 2013 | DSM-IV | n/a | Clinical interview, questionnaire | Excluded | 49 | 49 | 55.2 | 55.2 | 69.4 | 70 | Excluded | n/a | n/a | n/a |
| Noh et al., 2012 | ICSD-2 | 7.6 years | Clinical interview | Excluded | 20 | 20 | 90 | 90 | 50.8 | 50.4 | Excluded | Excluded | Excluded | n/a |
| Perrier et al., 2015 | DSM-IV | n/a | Clinical interview, questionnaire | Excluded | 21 | 16 | 57.1 | 62.5 | 48.7 | 48.3 | Excluded | n/a | n/a | PM |
| Randazzo et al., 2000 | DSM-IV | n/a | n/a | Excluded | 35 | 35 | 71.4 | 77.1 | 43.6 | 43.5 | n/a | n/a | n/a | n/a |
| Rosa and Bonnet, 2000 | SOL>45 or WASO>60 min, 4 nights per week for 1 year | 7.9 years | Questionnaire, psg | Excluded | 121 | 56 | 38 | 32 | 35 | 36 | Excluded | Excluded | n/a | Repeated testing |
| Sagaspe et al., 2007 | ICSD-2 | >6 months | Clinical interview, psg | n/a | 13 | 13 | 38.4 | 38.4 | 47.4 | 47.4 | Excluded | n/a | n/a | PM |
| Son et al., 2018 | DSM-5 | 4.9 years | Clinical interview, questionnaire | Excluded | 21 | 26 | 57.1 | 57.7 | 36.6 | 33.2 | Excluded | n/a | n/a | AM |
| Shekleton et al., 2014 | RDC | n/a | Clinical interview, questionnaire | Excluded | 76 | 20 | 57.8 | 70 | 35.7 | 34.7 | Excluded | Excluded | n/a | Repeated testing |
| Siversten et al., 2013 | DSM-IV | n/a | Questionnaire | Excluded | 30 | 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| Szelenberger and Niemcewicz, 2001 | DSM-IV | 8.2 years | Questionnaire, actigraphy, psg | Excluded | 14 | 14 | 57.1 | 57.1 | 41.2 | 36.2 | Excluded | n/a | n/a | AM |
| Varkevisser et al., 2007 | ICSD-2 | n/a | Clinical interview, diary | n/a | 39 | 20 | 58.9 | 50 | 40.9 | 42.6 | n/a | n/a | n/a | Repeated testing |
| Vignola et al., 2000 | ICSD, DSM-IV | n/a | Clinical Interview, questionnaire, diary | Excluded | 20 | 20 | 10 | 10 | 61.7 | 63.3 | Excluded benzodiazepine | n/a | n/a | AM |
AM, morning; DSM, diagnostic and statistical manual of mental disorders; ICD, international classification of diseases; ICSD, international classification of sleep disorders; n/a, not available; PM, afternoon/evening; PSG, polysomnography; RDC, research diagnostic criteria; SEI, sleep efficiency index; SOL, sleep onset latency; TST, total sleep time, WASO, wake after sleep onset. X = no group differences,
excluded if could impact cognitive function or reaction times.