Figure 7.
Enteropathy induced by p31-43 requires NLRP3 and caspase 1. Morphological analysis of proximal small intestine of C57BL/6, NLRP3−/−, and caspase 1−/− mice, 16 h after oral administration of 20 μg p31-43 or PBS, showing mean IEL/100 enterocytes (left axis) and villus/crypt ratios (right axis). Results shown are means ± 1 SEM for 6 mice/group. *p < 0.05.