Figure 5.

SOX9 is localized in the wool follicle pegs and apocrine sweat glands (red dashed line). (A) SOX9 is expressed in the placodes of primary wool follicles and occasionally in the basal layer; (B) As the primary wool follicles grow downward into the dermis, SOX9 is strongly expressed in the primary wool follicle pegs and basal layer, and weakly in the precursor cells of the apocrine sweat glands; (C–D) SOX9 is expressed in the apocrine sweat gland budding point (C) and buds (D), and also in wool follicle pegs. (E) SOX9 is strongly expressed in the ducts of apocrine sweat glands. It is also expressed in the elongated epidermal compartments of wool follicles. (F) The negative control is displayed without applying the primary antibody in immunohistochemistry. A–D Bar, 50 μm. E and F Bar, 100 μm.