Table 2.

Characteristics and statistics for the 12 CpGs in the CRACR2A gene associated with weekly vigorous physical activity frequency.

Probe ID	Genome Coordinate	In DMR	Gene annotation	Mean beta(exercise <=1, exercise>1)	Adjusted difference in beta†	DMP p-value	Correlation with mRNA expression
cg09172548	3732482	Yes	1st Exon; 5’ UTR	(0.40, 0.32)	−0.047	0.06	−0.34
cg04804877	3732486	Yes	1st Exon; 5’ UTR	(0.38, 0.29)	−0.057	0.03	−0.35
cg0819230	3732678	Yes	TSS200	(0.37,0.29)	−0.050	0.01	−0.35
cg03397307	3732684	Yes	TSS200	(0.38,0.28)	−0.061	0.01	−0.34
cg16133088	3732689	Yes	TSS200	(0.39,0.31)	−0.054	0.01	−0.35
cg05972871	3732705	Yes	TSS200	(0.37,0.28)	−0.060	0.02	−0.34
cg26955987	3732718	Yes	TSS200	(0.40, 0.31)	−0.060	0.03	−0.33
cg03485694	3732734	Yes	TSS200	(0.42, 0.35)	−0.044	0.01	−0.34
cg12710510	3732758	Yes	TSS200	(0.41,0.32)	−0.060	0.004	−0.33

^†the difference in beta estimated in linear regression adjusted for potential confounders.