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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: J Immunol. 2019 Jan 9;202(4):1033–1038. doi: 10.4049/jimmunol.1801438

Figure 3. The P2rx7 gene locus is repressed by HDAC3 in DP thymocytes.

Figure 3.

(A) ChIP-seq and CapSTARR-seq snapshots at P2rx7, Cd8a, and Hoxc7. Yellow boxes identify previously characterized promoter (P) and enhancer (E) regions (32). (B) HDAC3 qChIP at the P2rx7 promoter and enhancer in DP thymocytes from WT and HDAC3-cKO mice. Plots show mean ± SEM of 3–4 mice per group from 3 independent experiments. (C) H3K27ac qChIP at the P2rx7 enhancer in DP thymocytes from WT and HDAC3-cKO mice. Plots show mean ± SEM of 3 mice per group from 3 independent experiments.